Janusz Blasiak Selected Research

Drug Therapy (Chemotherapy)

4/2016	Role of the Cell Cycle Re-Initiation in DNA Damage Response of Post-Mitotic Cells and Its Implication in the Pathogenesis of Neurodegenerative Diseases.
11/2006	Antioxidant properties of trans-3,3',5,5'-tetrahydroxy-4'-methoxystilbene against modification of variety of biomolecules in human blood cells treated with platinum compounds.
10/2004	Basal, oxidative and alkylative DNA damage, DNA repair efficacy and mutagen sensitivity in breast cancer.
1/2003	Hyperthermia can differentially modulate the repair of doxorubicin-damaged DNA in normal and cancer cells.
11/2002	DNA damage and repair in BCR/ABL-expressing cells after combined action of idarubicin, STI571 and amifostine.

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Janusz Blasiak Research Topics

Disease

44	Neoplasms (Cancer) 10/2021 - 11/2002
27	Macular Degeneration (Age-Related Maculopathy) 05/2022 - 10/2009
16	Breast Neoplasms (Breast Cancer) 03/2022 - 01/2003
14	Leukemia 02/2011 - 01/2002
12	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2017 - 03/2003
10	Genomic Instability 05/2020 - 01/2003
7	Inflammation (Inflammations) 11/2020 - 11/2012
5	Migraine Disorders (Migraine) 06/2022 - 11/2019
5	Neoplasm Metastasis (Metastasis) 03/2022 - 01/2006
4	Carcinogenesis 09/2015 - 04/2010
4	Keratoconus 10/2014 - 01/2013
4	Infections 08/2013 - 02/2005
3	Fuchs' Endothelial Dystrophy 08/2014 - 01/2013
3	Philadelphia Chromosome 01/2013 - 01/2002
3	Colorectal Neoplasms (Colorectal Cancer) 01/2012 - 01/2008
2	Pain (Aches) 05/2022 - 06/2013
2	Geographic Atrophy 05/2022 - 05/2016
2	Choroidal Neovascularization 05/2022 - 07/2013
2	Alzheimer Disease (Alzheimer's Disease) 05/2019 - 04/2016
2	Xeroderma Pigmentosum (Kaposi's Disease) 01/2017 - 07/2009
2	Eye Diseases (Eye Disease) 04/2016 - 01/2013
2	Colonic Neoplasms (Colon Cancer) 01/2012 - 08/2011
2	Dyspepsia (Indigestion) 06/2011 - 03/2007
2	Endometrial Neoplasms (Endometrial Cancer) 02/2011 - 04/2010
2	Myeloid Leukemia (Leukemia, Myelocytic) 04/2009 - 01/2003
2	Type 2 Diabetes Mellitus (MODY) 06/2008 - 10/2004
2	Diabetic Retinopathy (Retinopathy, Diabetic) 04/2008 - 01/2008
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 03/2003 - 06/2002
2	Genetic Translocation (Chromosomal Translocation) 03/2003 - 06/2002

Drug/Important Bio-Agent (IBA)

39	DNA (Deoxyribonucleic Acid)IBA 06/2022 - 01/2003
23	Proteins (Proteins, Gene)FDA Link 06/2022 - 01/2003
11	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2022 - 06/2008
10	Imatinib Mesylate (Gleevec)FDA Link 01/2016 - 11/2002
9	Phosphotransferases (Kinase)IBA 05/2022 - 06/2002
8	MelatoninIBA 12/2021 - 05/2005
8	AntioxidantsIBA 01/2021 - 05/2005
8	Pharmaceutical PreparationsIBA 08/2011 - 01/2003
6	MicroRNAs (MicroRNA)IBA 05/2022 - 01/2012
6	Estrogens (Estrogen)FDA Link 11/2017 - 01/2006
6	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 04/2016 - 10/2004
5	Retinaldehyde (Retinal)IBA 05/2016 - 10/2009
5	EnzymesIBA 04/2016 - 02/2003
5	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2016 - 01/2002
4	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 10/2021 - 06/2002
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2020 - 01/2008
4	IronIBA 01/2015 - 01/2011
4	MutagensIBA 08/2013 - 10/2004
4	Amifostine (Ethyol)FDA LinkGeneric 07/2007 - 11/2002
3	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 06/2022 - 01/2006
3	Vitamin D FDA LinkGeneric 03/2022 - 04/2016
3	VitaminsIBA 12/2021 - 01/2019
3	Telomerase (Telomerase Reverse Transcriptase)IBA 07/2021 - 01/2014
3	AntigensIBA 01/2021 - 01/2006
3	Mitochondrial DNA (mtDNA)IBA 11/2020 - 01/2014
3	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2019 - 02/2003
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 08/2013
3	Cisplatin (Platino)FDA LinkGeneric 08/2014 - 04/2004
3	Transferrin (beta 2 Transferrin)IBA 01/2013 - 01/2011
3	Methylnitronitrosoguanidine (MNNG)IBA 02/2011 - 01/2008
3	Progesterone Receptors (Progesterone Receptor)IBA 08/2009 - 01/2006
3	Codon (Codons)IBA 07/2009 - 12/2005
3	Free RadicalsIBA 04/2009 - 04/2004
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2006 - 01/2003
3	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2006 - 11/2002
3	Tyrosine (L-Tyrosine)FDA Link 03/2003 - 06/2002
2	Calcitonin Gene-Related PeptideIBA 05/2022 - 09/2021
2	Proteasome Endopeptidase Complex (Proteasome)IBA 05/2022 - 01/2019
2	Serine (L-Serine)FDA Link 05/2022 - 05/2006
2	UbiquitinIBA 05/2022 - 01/2019
2	NF-kappa B (NF-kB)IBA 05/2022 - 04/2018
2	Long Noncoding RNAIBA 03/2022 - 11/2017
2	Cholecalciferol (Vitamin D3)FDA Link 03/2022 - 04/2016
2	Caffeine (No Doz)FDA LinkGeneric 12/2021 - 05/2006
2	Folic Acid (Vitamin M)FDA LinkGeneric 12/2021 - 11/2019
2	IonsIBA 12/2021 - 01/2011
2	Tryptophan (L-Tryptophan)FDA Link 09/2021 - 10/2020
2	ElementsIBA 11/2020 - 04/2009
2	ZincIBA 07/2020 - 04/2009
2	Adenosine Triphosphate (ATP)IBA 01/2019 - 08/2013
2	Transcription Factors (Transcription Factor)IBA 04/2018 - 09/2015
2	Matrix Metalloproteinases (MMPs)IBA 11/2017 - 01/2006
2	Estrogen ReceptorsIBA 11/2017 - 09/2015
2	DNA-Activated Protein KinaseIBA 01/2017 - 08/2014
2	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 01/2017 - 08/2014
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 01/2017 - 05/2006
2	Tyrosine Kinase InhibitorsIBA 01/2013 - 04/2004
2	heme oxygenase-2IBA 03/2012 - 08/2011
2	8-hydroxyguanineIBA 12/2009 - 07/2009
2	bcr-abl Fusion ProteinsIBA 01/2006 - 12/2004
2	CarcinogensIBA 02/2005 - 02/2005
2	Free Radical ScavengersIBA 04/2004 - 02/2003
2	Anaplastic Lymphoma KinaseIBA 03/2003 - 06/2002
1	TRPA1 Cation ChannelIBA 06/2022
1	Histone Deacetylase 6IBA 05/2022
1	AntibodiesIBA 05/2022
1	CalciumIBA 05/2022
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 05/2022

Therapy/Procedure

23	Therapeutics 05/2022 - 11/2002
5	Drug Therapy (Chemotherapy) 04/2016 - 11/2002
2	Aftercare (After-Treatment) 05/2006 - 10/2004